By Shakoor Rather :
THE presence of antibodies indicates previous exposure to the SARS-CoV-2 virus but may not always translate into protection against the disease, say scientists, citing imponderables such as what kind of antibodies, how many and how long they last. As worries over India’s COVID-19 spike mount – the country added 90,062 cases on Monday to take its tally past the 42-lakh mark – scientists are grappling with the pivotal issue of antibodies and trying to understand how they impact on the progression of the disease. But the jury is still out there with several studies and hypotheses but no consensus yet.
The only thing that can be said with any degree of uncertainty is that antibodies is a sign that the person has already been infected with the novel coronavirus, the scientists said. Immunologist Satyajit Rath said, he would prefer to “wait and see” where the evidence goes. Antibody presence in itself tells us nothing about disease progression in individuals, said the scientist from New Delhi’s National Institute of Immunology (NII). There are neutralising antibodies (nAbs) and also ‘simple’ antibodies.
While nAbs produced against the novel coronavirus can block its entry into the host cell, other antibodies are also generated against many parts of the virus, added Vineeta Bal from Pune’s Indian Institute of Science, Education and Research (IISER). The ‘simple’ antibodies are an indication of host response to viral presence but are not that useful to stop further spread of the virus, Bal told PTI. “Simple presence of antibodies is a clear indication of previous exposure to SARS-CoV2 but does not necessarily guarantee protection from the disease in the absence of neutralising antibodies,” the immunologist added.
“Presence of nAbs in sufficient concentrations and for longer period is the most likely indicator of protection of the individual from next exposure leading to illness i.e. COVID-19,” she explained. Different sero-survey tests have been conducted in India in the last few months with the aim of indicating the actual number of infected cases in the country. A sero-survey involves testing the blood serum of a group of individuals for the presence of antibodies against that infection to know who has been infected in the past and has now recovered. Surveys carried across metros suggest that COVID-19 cases are far more than actually reported.
Corona Cards - A new fraud in market
AFTER wearing masks, maintaining social distancing and drinking the staple ‘kadha’, a new anti-coronavirus item has arrived in the market and people are flocking to buy it. This is the COVID-19 ‘shut-out’ card that looks like a small ID, which is to be worn around the neck. The card claims that it wards off the virus and if a person wears the card around his neck, he/she can stay safe in the pandemic. The card is priced between Rs 200 and 400, depending on the ‘quality’.
“The cards are being sold in large numbers because people feel it is the easiest way to ward off the virus. The cards that we are selling have a three-month expiry date,” said Ravi Krishna, a salesman at a medical shop in Luckow’s Narhi area. The cards are also available on e-commerce website and are priced at around Rs 60 with an expiry date of 30 days. Medical practitioners have however, rubbished the claims made by companies manufacturing these cards calling it a ‘major fraud’.